Schedule 2008-09 |
June
|
5 (Thurs) |
Dr. Bhagwati Gupta
Department of Biology, McMaster University
A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans (Insuk et al., Nature Genetics 2008, vol. 40, p. 181-188) PDF
|
19 (Thurs) |
Dr. Andre Bedard
Department of Biology, McMaster University
PTEN Nuclear Localization Is Regulated by Oxidative Stress and Mediates p53-Dependent Tumor Suppression (Chang et al., Mol. Cell. Biol. 2008, vol. 28, p. 3281-3289) PDF
Ubiquitination Regulates PTEN Nuclear Import and Tumor Suppression (Trotman et al., Cell 2007, vol. 128, 141-156) PDF
|
July
|
10 (Thurs) |
Nickett Donaldson
Daniel lab
Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions (Zeng et al., Development 2008, vol. 135, 367-375)
|
31 (Thurs) |
Kim Glenfield
Zhu lab
Cell cycle control of telomere protection and NHEJ revealed by a ts mutation in the DNA-binding domain of TRF2 (Konishi and de Lange, Genes & Development 2008, vol. 22:1221-1230)
|
August
|
14 (Thurs) |
Michelle Anstey
Zhu lab
Cyclical DNA methylation of a transcriptionally active promoter (Metivier et al., Nature 2008, vol. 452, 45-50)
|
September
|
11th (Thurs) |
Jenny Wang
Bedard lab
A robust system for RNA interference in the chicken using a modified microRNA operon (Das et al., Developmental Biology 2006, vol. 294, 554-563)
|
October
|
23rd (Thurs) |
Noor Hossain
Jacobs lab
The Tumor Suppressors Merlin and Expanded Function Cooperatively to Modulate Receptor Endocytosis and Signaling (Maitra et al., Current Biology 2006, vol. 16, 702-709)
|
December
|
18th (Thurs) |
Megan McKerlie
Zhu lab
-Postponed-
|
January
|
8th (Thurs)# HSC-1A03 |
Dr. Alex Schumacher
Technical University of Munich, Germany
Complex diseases, environment and the emerging epigenetic paradigm: Lessons from neurobehavioral disorders Abstract
|
23rd (Fri) |
Megan McKerlie
Zhu lab
Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance (Lee et al., Nature Cell Biology, 2008, vol. 11, pp. 97-105) PDF
|
February
|
6th (Fri) |
-OPEN-
|
20th (Fri) |
Dr. Chris Wynder
McMaster Stem Cell Research Institute
Transcriptional regulation via H3K4 methylation; how do you decide? Abstract
|
March
|
6th (Fri) |
Kyster Nanan
Daniel lab
An essential role for p120-catenin in Src- and Rac1-mediated anchorage-independent cell growth (Dohn et al. 2009, JCB, vol. 184, No. 3, 437-450) PDF
|
20th (Fri) |
Bart Maslikowski
Bedard lab
Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function (Cheng et al. 2003, JBC, vol. 283, 14665-14673) PDF
|
April
|
3rd (Fri) |
Judith West-Mays - Postponed-
Pathology & Molecular Medicine, McMaster Health Sciences
Role of AP-2 genes in ocular development and congenital disease
|
24th (Fri) |
Chistine Kerr
West-Mays lab
Lens Defects Resulting From Activated Smoothened Mutation Mimicking Constitutive Hedgehog Signaling
|
May
|
1st (Fri) |
Michelle Melone
Daniel lab
p120 Catenin Recruits Cadherins to (gamma)-Secretase and Inhibits Production of A(beta) Peptide (Kouchi et al. 2009, JBC, vol. 284, 1954-1961) PDF
|
15th (Fri) |
Aidan Dineen
Campos lab
A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death (Saijo et al. 2009, Cell, vol. 137, 47-59) PDF
|
29th (Fri) |
Jillian Roberts
Fahnestock lab
Brain-derived neurotrophic factor downregulation in Alzheimer's disease: Is tau involved?
|