Molecular, Cell, Development (MCD) Seminar Series - McMaster University
2008-09 || 2009-10 || 2010-11 || 2011-12 || 2012-13

Molecular, Cell, Development (MCD) SEMINAR SERIES
Department of Biology

Schedule 2010-11
10th (Fri) Dr. Pierre McCrea -Cancelled-
MD Anderson Cancer Center and University of Texas at Houston

Networked Wnt-signaling roles of distinct catenins in vertebrates

24th (Fri) Dr. Senthil Muthuswamy
Princess Margaret Hospital, Toronto

Dr. Muthuswamy's research is focused on treatment and control of premalignant breast cancer lesions and understanding how cell architecture, specifically cell polarity, is disrupted during cancer development. Dr. Muthuswamy uses a combination of mouse models and a unique organotypic 3-dimensional, cell culture method to study how cell polarity proteins and pathways regulate normal morphogenesis and how cell polarity disruption initiates cancer.

8th (Fri) Dr. David Andrews
Department of Biochemistry and Biomedical Sciences

Dr. Andrews' research is focused primarily in four areas: Protein Targeting, Apoptosis, Cell Adhesion, and Cancer.

22nd (Fri) Dr. Bruce Reed
Department of Biology, University of Waterloo

Dr. Reed's research is focused on understanding how cells are genetically programmed to die when they lose contact with their surroundings. The failure of this type of cell death (known as anoikis) contributes to cancer metastasis and tumour invasiveness in humans. Dr. Reed uses green fluorescent protein (GFP)-based methods of live imaging in the model genetic organism Drosophila (the fruit fly) to study anoikis.

5th (Fri) Dr. Karen Mossman
Department of Pathology and Molecular Medicine, McMaster University

Dr. Mossman's research is focused on elucidating how viruses evade host immune defenses via interferon inhibition and on the development of viruses for use in gene therapy and cancer therapy. Her research focuses on targeting the herpes simplex virus type 1 (HSV-1) to cancer cells where they can grow and kill these cells while having no effect on healthy cells. Such viruses, called "oncolytic viruses" are currently being tested as a novel approach to cancer therapy in the hopes of eliminating tumors without the toxic side effects associated with many current treatments.

19th (Fri) Dr. Sheila Singh
Department of Surgery, McMaster University

3rd (Fri) Dr. Jonathan Bramson
Centre for Gene Therapeutics and Department of Pathology and Molecular Medicine, McMaster University

The Bramson lab studies T cell and B cell immunity using a variety of cutting-edge methodologies, including multi-parametric flow cytometry and phage display. Through collaboration, Dr. Bramson has taken a multi-disciplinary approach to his challenges that employs biological, mathematical and epidemiological concepts. He is specifically interested in optimizing the application of recombinant adenovirus vaccines, developing novel immunotherapies for cancer, and understanding the impact of ageing on immune function.

17th (Fri) Dr. Dorothea Godt
Department of Cell and Systems Biology, University of Toronto

Dr. Godt's research is focused on investigating the molecules that govern cell morphogenesis during the development of the ovary in Drosophila melanogaster. Her current work focuses on the function of several morphogenetic regulators, such as adhesion molecules of the cadherin family.

14th (Fri) Dr. Gurmit Singh
Pathology and Molecular Medicine, McMaster University

Intercellular communication in bone metastasis. Abstract

28th (Fri) Dr. Vojislava Grbic
Department of Biology, University of Western Ontario

The genomics of herbivore-plant interaction: whole genome sequence of Tetranychus urticae provides novel genomic tools for dissecting plant-pest relationship. Abstract

11th (Fri) Dr. Gabrielle Boulianne
Hospital for Sick Children in Toronto

Using Fruit Flies to Unlock the Secrets of Longevity. Abstract

25th (Fri) Dr. Hsiao-Huei Chen
Ottawa Hospital Research Institute and Department of Medicine, University of Ottawa

Obesity and dementia: it's what happens when LMO4 is deleted in the brain. Abstract

8th (Fri) Dr. Michael Ohh
Department of Medicine, University of Toronto

Modern concepts in polycythemia from a 100 year-old syndrome. Abstract