Molecular, Cell, Development (MCD) Seminar Series - McMaster University
2008-09 || 2009-10 || 2010-11 || 2011-12 || 2012-13

Molecular, Cell, Development (MCD) SEMINAR SERIES
Department of Biology

Speaker: Dr. Ashley Bruce

Date: Friday April 5th, 2013
Time: 12 noon
Location: HSC 1A5

Title: Thinning and spreading: How the zebrafish embryo gets into shape.

Work in the lab addresses how the complex and varied body plans of animals are generated during embryonic development with the long-term goal of understanding how coordinated cell movements and embryonic tissue patterning are linked. Our approach is to use a combination of cellular, molecular and embryological techniques to study these questions in the zebrafish embryo. We focus on epiboly, or the thinning and spreading of a multilayered cell sheet, as a model system for cell rearrangement. Epiboly is used during development in many species, though we still lack a good understanding of the cellular and molecular mechanisms that underlie it. I will present work from the lab examining the mechanisms of epiboly control in zebrafish.