Molecular, Cell, Development (MCD) Seminar Series - McMaster University
2008-09 || 2009-10 || 2010-11 || 2011-12 || 2012-13

Molecular, Cell, Development (MCD) SEMINAR SERIES
Department of Biology

Speaker: Justin Tong (Gupta Lab, McMaster University)

Date: Friday, September 14, 2012
Time: 12 noon
Location: HSC 1A5

Title: A Microfluidic Platform for Chemical Screening in C. elegans

A method to induce and quantify on-demand locomotion in nematode Caenorhabditis elegans is here demonstrated in a novel assay for neurobehavioural chemical toxicity. We employ the assay in two contexts: a toxicological investigation of environmental pollutants, and a drug discovery screen of a compound library. Using electric fields and microfluidic technology, our assay is a rapid, sensitive, low-cost, and scalable technique to screen for factors affecting neuronal health.